Medical & Healthcare

Before any model reasons, the companion builds the brief with you. Patient profile. Therapeutic context. Regulatory jurisdiction. Level of evidence required. You approve it. The deliberation starts from your clinical reality.

• ·PubMed — peer-reviewed biomedical literature
• ·Cochrane Reviews — systematic reviews and meta-analyses
• ·ClinicalTrials.gov — active and completed trial data
• ·WHO — international clinical guidelines
• ·EMA — EU drug approvals and safety alerts
• ·NICE — UK clinical guidelines
• ·HAS — French health authority recommendations
• ·FDA — drug approvals and safety communications
• ·bioRxiv / medRxiv — emerging research

Every claim carries a provenance tag. [SOURCED] means traced to a verified reference. [INFERRED] means analytical inference — flagged automatically.

• The Architect maps the clinical pathway and protocol feasibility.
• The Strategist reads epidemiological signals and treatment landscape trends.
• The Engineer examines biological feasibility and methodology rigor.
• The Counsel surfaces regulatory exposure, liability, and patient safety obligations.
• The Contrarian sole mandate: challenge every clinical assumption and every study cited.

Five complete analyses. Five distinct angles. Not five versions of the same answer. Then they challenge each other — anonymously. Then they converge.

Output: GO / PIVOT / STOP · Confidence score · Decision matrix · Minority Report · Testable predictions.

Questions Pilot5.ai helps with

• What does the evidence say about this treatment for this patient profile?
• Should we adopt this protocol given the latest Phase III data?
• How do HAS and NICE guidelines differ on this indication?
• Our trial has a design flaw. Should we proceed to publication?